{"id":1180,"date":"2020-04-14T08:08:22","date_gmt":"2020-04-14T08:08:22","guid":{"rendered":"https:\/\/fondvlongo.wpengine.com\/demo\/cancro-for-doctors\/"},"modified":"2024-05-30T17:47:05","modified_gmt":"2024-05-30T15:47:05","slug":"cancer-for-doctors","status":"publish","type":"page","link":"https:\/\/www.fondazionevalterlongo.org\/en\/cancer-for-doctors\/","title":{"rendered":"Cancer"},"content":{"rendered":"

Cancro<\/h1>\n
\n

For further information, please refer to the following scientific papers.<\/p>\n

\n
\n
\n

INTERNATIONAL JOURNAL OF CANCER\/2024<\/strong><\/p>\n

Ligorio, Francesca et al. \u201cAdding fasting-mimicking diet to first-line carboplatin-based chemotherapy is associated with better overall survival in advanced triple-negative breast cancer patients: A subanalysis of the NCT03340935 trial.\u201d\u00a0International journal of cancer<\/em>\u00a0vol. 154,1 (2024): 114-123. doi:10.1002\/ijc.34701<\/a><\/p>\n

CANCER RESEARCH\/2024<\/strong><\/p>\n

Raucci, Franca et al. \u201cCyclic Fasting-Mimicking Diet Plus Bortezomib and Rituximab Is an Effective Treatment for Chronic Lymphocytic Leukemia.\u201d\u00a0Cancer research<\/em>\u00a0vol. 84,7 (2024): 1133-1148. doi:10.1158\/0008-5472.CAN-23-0295<\/a><\/p>\n

CANCERS\/2024<\/strong><\/p>\n

Buono, Roberta et al. \u201cFasting-Mimicking Diet Inhibits Autophagy and Synergizes with Chemotherapy to Promote T-Cell-Dependent Leukemia-Free Survival.\u201d\u00a0Cancers<\/em>\u00a0vol. 15,24 5870. 16 Dec. 2023, doi:10.3390\/cancers15245870<\/a><\/p>\n

EUROPEAN JOURNAL OF CANCER\/2022<\/strong><\/p>\n

Ligorio, Francesca et al. \u201cExceptional tumour responses to fasting-mimicking diet combined with standard anticancer therapies: A sub-analysis of the NCT03340935 trial.\u201d\u00a0European journal of cancer (Oxford, England : 1990)<\/em>\u00a0vol. 172 (2022): 300-310. doi:10.1016\/j.ejca.2022.05.046<\/a><\/p>\n

CELL REPORTS\/2022<\/strong><\/p>\n

Cortellino, Salvatore et al. \u201cFasting renders immunotherapy effective against low-immunogenic breast cancer while reducing side effects.\u201d\u00a0Cell reports<\/em>\u00a0vol. 40,8 (2022): 111256. doi:10.1016\/j.celrep.2022.111256<\/a><\/p>\n

AGING CELL\/2022<\/strong><\/p>\n

Rahmani, Jamal et al. \u201cAssociation between IGF-1 levels ranges and all-cause mortality: A meta-analysis.\u201d\u00a0Aging cell<\/em>\u00a0vol. 21,2 (2022): e13540. doi:10.1111\/acel.13540<\/a><\/p>\n

CANCER DISCOVERY\/2022<\/strong><\/p>\n

Vernieri, Claudio et al. \u201cFasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer.\u201d\u00a0Cancer discovery<\/em>\u00a0vol. 12,1 (2022): 90-107. doi:10.1158\/2159-8290.CD-21-0030<\/a><\/p>\n

CANCERS\/2021<\/strong><\/p>\n

Valdemarin, Francesca et al. \u201cSafety and Feasibility of Fasting-Mimicking Diet and Effects on Nutritional Status and Circulating Metabolic and Inflammatory Factors in Cancer Patients Undergoing Active Treatment.\u201d\u00a0Cancers<\/em>\u00a0vol. 13,16 4013. 9 Aug. 2021, doi:10.3390\/cancers13164013<\/a><\/p>\n

NATURE\/2020<\/strong><\/p>\n

Caffa, Irene et al. \u201cAuthor Correction: Fasting-mimicking diet and hormone therapy induce breast cancer regression.\u201d\u00a0Nature<\/em>\u00a0vol. 588,7839 (2020): E33. doi:10.1038\/s41586-020-2957-6<\/a><\/p>\n

BREAST CANCER RESEARCH AND TREATMENT\/2021<\/strong><\/p>\n

Lugtenberg, Rieneke T et al. \u201cQuality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT (BOOG 2013-14) trial.\u201d\u00a0Breast cancer research and treatment<\/em>\u00a0vol. 185,3 (2021): 741-758. doi:10.1007\/s10549-020-05991-x<\/a><\/p>\n

NATURE COMMUNICATIONS\/2020<\/strong><\/p>\n

de Groot, Stefanie et al. \u201cFasting mimicking diet as an adjunct to\u2009neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial.\u201d\u00a0Nature communications<\/em>\u00a0vol. 11,1 3083. 23 Jun. 2020, doi:10.1038\/s41467-020-16138-3<\/a><\/p>\n

NATURE COMMUNICATIONS\/2020<\/strong><\/p>\n

Di Tano, Maira et al. \u201cSynergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers.\u201d\u00a0Nature communications<\/em>\u00a0vol. 11,1 2332. 11 May. 2020, doi:10.1038\/s41467-020-16243-3<\/a><\/p>\n

Nature Review Cancer \/\u00a02018<\/strong>
\nFasting and cancer: molecular mechanisms and clinical application.<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
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BMC CANCER \/\u00a02018<\/strong>
\nThe effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study<\/a><\/p>\n

Stephan P. Bauersfeld1, Christian S. Kessler1,2, Manfred Wischnewsky3, Annette Jaensch2, Nico Steckhan1, Rainer Stange1,2, Barbara Kunz2, Barbara Br\u00fcckner4, Jalid Sehouli5 and Andreas Michalsen1,2<\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
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JOP. Journal of the Pancreas \/\u00a02018<\/strong>
\nLong-Term Outcomes of the Treatment of Unresectable (StageIII- IV) Ductal Pancreatic Adenocarcinoma Using Metabolically Supported Chemotherapy (MSCT): A Retrospective Study<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
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CELL PRESS \/\u00a02018<\/strong>
\nStarvation, Stress Resistance, and Cancer<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
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SCIENTIFIC REPORTS \/ 2017<\/strong>
\nEffects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
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PLOS|BIOLOGY \/\u00a0<\/strong>2017<\/strong><\/p>\n

Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
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ELSEVIER \/ 2017<\/strong>
\nProtective effects of short-term dietary restriction in surgical stress and chemotherapy<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
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SCIENTIFIC REPORTS \/ 2017<\/strong>
\nEffects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

AACR \/ 2016<\/strong>
\nTargeting Cancer Metabolism: Dietary and Pharmacologic Interventions<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

BIOMED CENTRAL \/ 2016<\/strong>
\nSafety and feasibility of fasting in combination with platinum based chemotherapy<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

CELL PRESS \/ 2016<\/strong>
\nFasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

ELSEVIER \/ 2016<\/strong>
\nGrowth factors, aging and age-related diseases<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

BMC CANCER \/ 2015<\/strong>
\nThe effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study<\/a><\/p>\n

Stefanie de Groot1, Maaike PG Vreeswijk2, Marij JP Welters1, Gido Gravesteijn2, Jan JWA Boei2, Anouk Jochems1, Daniel Houtsma3, Hein Putter4, Jacobus JM van der Hoeven1, Johan WR Nortier1, Hanno Pijl5 and Judith R Kroep1<\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

IMPACT JOURNALS \/ 2015<\/strong>
\nFasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
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IMPACT JOURNALS \/ 2015<\/strong>
\nFasting induces anti-warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

ELSEVIER \/ 2013<\/strong>
\nShort-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

DISCOVER \/ 2013<\/strong>
\nA small group of Ecuadorians with rare genetic disorder could hold a key to cancer and other age-related illness.<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

NATIONAL INSTITUTE OF HEALTH \/ 2013<\/strong>
\nAging, Nutrient Signaling, Hematopoietic Senescence, and Cancer<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

SCIENCE TRANSLATIONAL MEDICINE \/ 2012<\/strong>
\nFasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

ELSEVIER \/ 2012<\/strong>
\nStarvation, detoxification, and multi drug resistance in cancer therapy<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

PLOS \/ 2012<\/strong>
\nFasting Enhances the Response of Glioma to Chemo and Radiotherapy<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

C Lee and VD Longo \/ 2011<\/strong>
\nFasting vs dietary restriction in cellular protection and cancer treatment:from model organisms to patients<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

JOVE \/ 2011<\/strong>
\nVideo ArticleStudying Age-dependent Genomic Instability using theS. cerevisiae Chronological Lifespan Model<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

CANCER RESEARCH \/ 2010<\/strong>
\nReduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fastingand Improve Chemotherapeutic Index<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

JCB \/ 2009<\/strong>
\nOncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1\/Pol-dependent mechanism<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

IMPACT AGING \/ 2009<\/strong>
\nFasting and cancer treatment in humans: A case series report<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

PNAS \/ 2008<\/strong>
\nStarvation-dependent differential stress resistanceprotects normal but not cancer cells againsthigh-dose chemotherapy<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

PERSPECTIVES \/ 2008<\/strong>
\nTurning anti aging genes against cancer<\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

JCB \/ 2008<\/strong>
\n Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner\/Bloom model system <\/a><\/p>\n<\/div>\n<\/section>\n

<\/div>\n
\n
\n

ELSEVIER \/ 2007<\/strong>
\n A simple model system for age-dependent DNA damage and cancer<\/a><\/p>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Cancro For further information, please refer to the following scientific papers. INTERNATIONAL JOURNAL OF CANCER\/2024 Ligorio, Francesca et al. \u201cAdding fasting-mimicking diet to first-line carboplatin-based chemotherapy is associated with better overall survival in advanced triple-negative breast cancer patients: A subanalysis of the NCT03340935 trial.\u201d\u00a0International journal of cancer\u00a0vol. 154,1 (2024): 114-123. doi:10.1002\/ijc.34701 CANCER RESEARCH\/2024 Raucci, Franca … <\/p>\n

Continue reading “Cancer”<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"patient.php","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-1180","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nCancer - Fondazione Valter Longo<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fondazionevalterlongo.org\/en\/cancer-for-doctors\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cancer - Fondazione Valter Longo\" \/>\n<meta property=\"og:description\" content=\"Cancro For further information, please refer to the following scientific papers. 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